Genetic Insights for Personalized Medicine

Avantra Genetics panels provide your healthcare professional with information about your unique genetics, which can be used to develop personalized treatments for difficult-to-treat conditions.

Our Services

Each of our Avantra Genetics panels provides healthcare professionals with full gene sequence information about genes that are related to the patient’s condition. The panels also report single location variants (SNPs) related to the patient’s condition and general wellness.

Migraine

$389

The Avantra Genetics Migraine Panel provides healthcare providers with genetic information that can be used to identify the best migraine management option. This is a great improvement over the typical trial-and-error approach, which can be time-consuming, expensive, and frustrating, considering the sizable list of migraine management options that are available.

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The Avantra Genetics Migraine Panel is a unique genetic sequencing service that looks at genes associated with disorders that feature migraine pain, including coenzyme Q10 deficiency, mitochondrial DNA depletion syndrome, advanced sleep-phase syndrome, dystonia, and others. The panel also looks at major biochemical pathways and receptors that can play a role. We take a novel approach by providing several types of clinical data for your healthcare professional to evaluate. We perform full-gene sequencing for 49 migraine-related genes, as well as looking at another 86 single locations (SNVs) related to migraines, plus another 85 single locations (SNPs) related to general wellness. The Avantra Genetics Migraine Panel is performed using the latest next-generation DNA sequencing technology in our CAP/CLIA certified laboratory.

 

Disease-related Full Gene Sequencing List: ATP1A2, ATP1A3, CACNA1A, CACNA1S, COQ2, COQ4, COQ6, COQ7, COQ8A, CSNK1D, GABBR2, GABRA1, GABRA2, GABRA3, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG2, GABRQ, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, GRIN3A, GRIN3B, GRINA, HTR1A, HTR2A, HTR3A, KCNK18, MAGT1, MR1, MTHFR, NOTCH3, PDSS1, PDSS2, POLG, PRRT2, SCN10A, SCN11A, SCN1A, SCN9A, SLC2A1, SLC52A1, SLC6A4, TRAP1

Disease-related SNV List: 1p31.1a, ACVRL1+, ARMS2–HTRA1, ASTN2+, c7orf10+, CACNA1A, CARF, CFDP1, EDNRA, ENG+, ESR1+, FHL5, FHL5–UFL1+, GRIA1+, GRIA3, HCRTR2, HCTR1+, HEY2–NCOA7, HPSE2, IGSF9B, KCNK18+, KCNN3, LRP1, LRP1–STAT6– SDR9C7, MEF2D+, MPPED2, MRVI1, MTDH, MTHFR+, NBEA, ADAMTSL4–ECM1~, CCM2L–HCK~, DOCK4–IMMP2L~, FGF6~, GJA1~, GPR149~, ITPK1~, JAG1~, MED14–USP9X~, NOTCH4~, REST–SPINK2~, TGFBR2~, TSPAN2–NGF~, WSCD1–NLRP1~, ZCCHC14~, NOS3, NRP1, NSDHL, PHACTR1+, PLCE1, PRDM16+, RNF213, RYR2+, SLC24A3, SLC6A4, STX1A+, TGFBR2, TNF, TRPM8, TRPM8–HJURP+, YAP1

General Wellness SNP List: AANT, ACAT1, ACE, ADM, AHCY+, BDNF, BHMT+, BTD, C5, CBS+, COMT+, CoQ2, CoQ3, COX5A, COX6C, CYP27A1, CYP27B1, DHFR, ENPP1, GSS, GSTM1, GSTP+, IGF1, IL10, IL23R, IL6, IL6R, KCNJ11, MAOA, MAOB, MAT1A, MAT2B, MTHFR+, MTR, MTRR+, NLRP6, NOS, NOS3, PDHA1, PDHB, PEMT, PNMT, PTPN22, PTS, QDPR, SHMT1+, SIRT1, SLC19A1, SLC22A5, SLC25A15, SLC25A32, SLC2A1, SOD2, SULT1A3, SUOX+, TGFB1+, TNF-alpha+, TRAF1, TRAP1, USF1, VDR+

 

Note: +:multiple variants sequenced for this gene, ~:intronic location near this gene

Abdominal Pain

Abdominal Pain

$389

The Avantra Genetics Abdominal Pain Panel looks for underlying genetic information related to difficult-to-treat chronic abdominal pain so that you and your healthcare professional can develop a personalized treatment plan based on your body’s unique genetics.

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The Avantra Genetics Abdominal Pain Panel is a unique genetic sequencing service that looks at genes associated with disorders that feature abdominal pain as a prominent symptom, such as celiac disease, lactase deficiency, hemochromatosis, porphyrias, lipoprotein disorders, and others. We take a novel approach by providing several types of clinical data for your healthcare professional to evaluate. We perform full-gene sequencing for over 35 genes related to abdominal pain, as well as looking at over 20 single locations (SNVs) related to abdominal pain, plus another 75 single locations (SNPs) related to general wellness. The Avantra Genetics Abdominal Pain Panel is performed using the latest next-generation DNA sequencing technology in our CAP/CLIA certified laboratory*.

 

Disease-related Full Gene Sequencing List: ABCC2, ABCG5, ABCG8, ACTG2, ALAD, APOA5, APOC2, CPOX, CTLA4, F12, FTH1, G6PD, GPIHBP1, HAMP, HFE, HFE2, HLA-DQA1, HLA-DQB1, HLA-DRB1, HMBS, LCT, LPL, MEFV, MYO9B, NLRP12, NLRP3, POLG, PPOX, SERPING1, SLC16A1, SLC40A1, SPINK1, TFR2, TNF, TNFRSF1A, TRAP1, TYMP

Disease-related SNV List: C1NH+, HBB+, GUCY2C, HMBS+, LPL+, MEFV+, NLRP3, RYR2

General Wellness SNP List: AANAT, ACAT1, ACE, ADM, AHCY+, BDNF, BHMT+, BTD, C5, CBS+, COMT+, CoQ2, CoQ3, COX5A, COX6C, CYP27A1, ENPP1, GSS, GSTM1, GSTP+, IGF1, IL10, IL23R, IL6, IL6R, KCNJ11, MAOA, MAOB, MAT1A, MAT2B, MTHFR+, MTR, MTRR+, NOS, NOS3, PDHA1, PDHB, PNMT, PTPN22, PTS, QDPR, SHMT1, SIRT1, SLC22A5, SLC25A15, SLC25A32, SLC2A1, SOD2, SUOX+, TGFB1+, TNF+, TRAF1, TRAP1, USF1, VDR+

 

Note: +:multiple variants sequenced for this gene, ~:intronic location near this gene

Autoinflammatory Panel

Autoinflammatory

$389

The Avantra Genetics Autoinflammatory Panel looks for underlying genetic information related to autoinflammatory symptoms (disorders of the innate immune system) so that you and your healthcare professional can develop a personalized treatment plan based on your body’s unique genetics.

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The Avantra Genetics Autoinflammatory Panel is a unique genetic sequencing service that looks at genes associated with autoinflammatory symptoms (disorders of the innate immune system), such as inflammatory bowel diseases, psoriaisis, periodic fever syndromes, acne inversa, and others. We take a novel approach by providing several types of clinical data for your healthcare professional to evaluate. We perform full-gene sequencing for over 35 genes related to inflammation, as well as looking at over 100 single locations (SNVs) related to inflammation, plus another 75 single locations (SNPs) related to general wellness. The Avantra Genetics Autoinflammatory Panel is performed using the latest next-generation DNA sequencing technology in our CAP/CLIA certified laboratory*.

 

Disease-related Full Gene Sequencing List: ABCB1, AP1S3, ATG16L1, CARD14, COPA, HLA-C, IL10, IL10RA, IL10RB, IL1RN, IL23A, IL23R, IL36RN, IL6, IRF5, IRGM, LPIN2, MEFV, MVK, NCSTN, NLRC4, NLRP12, NLRP3, NOD2, PLCG2, PSENEN, PSMB8, PSTPIP1, PTPN2, TMEM173, TNFAIP3, TNFRSF1A, TRAF3IP2

Disease-related SNV List: 1p31.1a, ACVRL1+, ARMS2–HTRA1, ASTN2+, c7orf10+, CACNA1A, CARF, CFDP1, EDNRA, ENG+, ESR1+, FHL5, FHL5–UFL1+, GRIA1+, GRIA3, HCRTR2, HCTR1+, HEY2–NCOA7, HPSE2, IGSF9B, KCNK18+, KCNN3, LRP1, LRP1–STAT6– SDR9C7, MEF2D+, MPPED2, MRVI1, MTDH, MTHFR+, NBEA, ADAMTSL4–ECM1~, CCM2L–HCK~, DOCK4–IMMP2L~, FGF6~, GJA1~, GPR149~, ITPK1~, JAG1~, MED14–USP9X~, NOTCH4~, REST–SPINK2~, TGFBR2~, TSPAN2–NGF~, WSCD1–NLRP1~, ZCCHC14~, NOS3, NRP1, NSDHL, PHACTR1+, PLCE1, PRDM16+, RNF213, RYR2+, SLC24A3, SLC6A4, STX1A+, TGFBR2, TNF, TRPM8, TRPM8–HJURP+, YAP1

General Wellness SNP List: AANT, ACAT1, ACE, ADM, AHCY+, BDNF, BHMT+, BTD, C5, CBS+, COMT+, CoQ2, CoQ3, COX5A, COX6C, CYP27A1, CYP27B1, DHFR, ENPP1, GSS, GSTM1, GSTP+, IGF1, IL10, IL23R, IL6, IL6R, KCNJ11, MAOA, MAOB, MAT1A, MAT2B, MTHFR+, MTR, MTRR+, NLRP6, NOS, NOS3, PDHA1, PDHB, PEMT, PNMT, PTPN22, PTS, QDPR, SHMT1+, SIRT1, SLC19A1, SLC22A5, SLC25A15, SLC25A32, SLC2A1, SOD2, SULT1A3, SUOX+, TGFB1+, TNF-alpha+, TRAF1, TRAP1, USF1, VDR+

 

Note: +:multiple variants sequenced for this gene, ~:intronic location near this gene

Nerve Pain

Neuropathic Pain

$389

The Avantra Genetics Neuropathic Pain Panel looks for underlying genetic information related to neuropathic pain (sensory neuropathies, episodic pain syndrome, paroxysmal extreme pain disorder, paroxysmal dyskinesia, porphyrias, and others) so that you and your healthcare professional can develop a personalized treatment plan based on your body’s unique genetics.

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The Avantra Genetics Neuropathic Pain Panel is a unique genetic sequencing service that looks at genes associated with disorders that feature neuropathic pain, such as sensory neuropathies, episodic pain syndrome, paroxysmal extreme pain disorder, paroxysmal dyskinesia, porphyrias, and others. The gene-sequencing panel also looks at select ion channels and receptors that are associated with neuropathic pain. We take a novel approach by providing several types of clinical data for your healthcare professional to evaluate. We perform full-gene sequencing for over 25 genes related to neuropathic pain, as well as looking at over 20 single locations (SNVs) related to neuropathic pain, plus another 75 single locations (SNPs) related to general wellness. The Avantra Genetics Neuropathic Pain Panel is performed using the latest next-generation DNA sequencing technology in our CAP/CLIA certified laboratory*.

 

Disease-related Full Gene Sequencing List:ALAD, CHRNA2, CLCN1, COX6A1, CPOX, DYNC1H1, GJB1, GLA, GLRA1, GRIA1, GRIA2, GRIA3, GRIA4, HMBS, KCNJ10, KCNMA1, MARS, MFN2, MPZ, NTRK1, PMP22, SCN10A, SCN11A, SCN4A, SCN9A, SEPT9, SPTLC1, TRPA1, TTR

Disease-related SNVs: ADRA1A+, ADRB2+, ADRB3, BDNF+, BDNF-AS+, C11orf40, CCDC190+, COMT, DNAJC16+, FAAH+, GRIA4, KCNS1, MAOA+, NGF, OPRD1+, OPRK1+, OPRM1+, P2RX7+, RYR2+, SLC6A4

General Wellness SNP List: AANAT, ACAT1, ACE, ADM, AHCY+, BDNF, BHMT+, BTD, C5, CBS+, COMT+, CoQ2, CoQ3, COX5A, COX6C, CYP27A1, ENPP1, GSS, GSTM1, GSTP+, IGF1, IL10, IL23R, IL6, IL6R, KCNJ11, MAOA, MAOB, MAT1A, MAT2B, MTHFR+, MTR, MTRR+, NOS, NOS3, PDHA1, PDHB, PNMT, PTPN22, PTS, QDPR, SHMT1, SIRT1, SLC22A5, SLC25A15, SLC25A32, SLC2A1, SOD2, SUOX+, TGFB1+, TNF+, TRAF1, TRAP1, USF1, VDR+

 

Note: +:multiple variants sequenced for this gene, ~:intronic location near this gene

Thyroid

Thyroid

$389

The Avantra Genetics Thyroid Panel looks for underlying genetic information related to thyroid dysregulation (abnormal thyroid hormone metabolism, hypothyroidism, thyroid hypoplasia, thyroid dyshormonogenesis, and others) so that you and your healthcare professional can develop a personalized treatment plan based on your body’s unique genetics.

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The Avantra Genetics Thyroid Panel is a unique genetic sequencing service that looks at genes associated with thyroid dysregulation, such as abnormal thyroid hormone metabolism, hypothyroidism, thyroid hypoplasia, thyroid dyshormonogenesis, and others. We take a novel approach by providing several types of clinical data for your healthcare professional to evaluate. We perform full-gene sequencing for over 25 genes related to thyroid dysregulation, as well as looking at over 15 single locations (SNVs) related to thyroid dysregulation, plus another 75 single locations (SNPs) related to general wellness. The Avantra Genetics Thyroid Panel is performed using the latest next-generation DNA sequencing technology in our CAP/CLIA certified laboratory*.

 

Disease-related Full Gene Sequencing List: ALB, CTLA4, DUOX2, DUOXA2, FOXE1, GNAS, IGSF1, IYD, NKX2-1, NKX2-5, PAX8, POU1F1, PROP1, SECISBP2, SERPINA7, SLC16A2, SLC26A4, SLC5A5, TG, THRA, THRB, TPO, TRHR, TSHB, TSHR, TTR

Disease-related SNV List: CAPZB, CD40, CTLA4+, DIO1, DIO2+, FCRL3+, FOXE1, FOXP3+, IFNG+, ITPR3, PDE8B+, SCGB3A2, SLCO1C1

General Wellness SNP List: AANAT, ACAT1, ACE, ADM, AHCY+, BDNF, BHMT+, BTD, C5, CBS+, COMT+, CoQ2, CoQ3, COX5A, COX6C, CYP27A1, ENPP1, GSS, GSTM1, GSTP+, IGF1, IL10, IL23R, IL6, IL6R, KCNJ11, MAOA, MAOB, MAT1A, MAT2B, MTHFR+, MTR, MTRR+, NOS, NOS3, PDHA1, PDHB, PNMT, PTPN22, PTS, QDPR, SHMT1, SIRT1, SLC22A5, SLC25A15, SLC25A32, SLC2A1, SOD2, SUOX+, TGFB1+, TNF+, TRAF1, TRAP1, USF1, VDR+

 

Note: +:multiple variants sequenced for this gene, ~:intronic location near this gene

General Wellness

$389

The Avantra Genetics General Wellness SNP Panel looks for underlying genetic information related to general wellness so that you and your healthcare professional can develop a personalized treatment plan based on your body’s unique genetics.

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The Avantra Genetics General Wellness SNP Panel is a unique genetic sequencing service that looks at 75 single genetic locations in pathways associated with general wellness, such as methylation, neurotransmitters, folate metabolism, lipids, and others. The Avantra Genetics General Wellness SNP Panel is performed using the latest next-generation DNA sequencing technology in our CAP/CLIA certified laboratory*.

 

 

General Wellness SNP List: AANAT, ACAT1, ACE, ADM, AHCY+, BDNF, BHMT+, BTD, C5, CBS+, COMT+, CoQ2, CoQ3, COX5A, COX6C, CYP27A1, ENPP1, GSS, GSTM1, GSTP+, IGF1, IL10, IL23R, IL6, IL6R, KCNJ11, MAOA, MAOB, MAT1A, MAT2B, MTHFR+, MTR, MTRR+, NOS, NOS3, PDHA1, PDHB, PNMT, PTPN22, PTS, QDPR, SHMT1, SIRT1, SLC22A5, SLC25A15, SLC25A32, SLC2A1, SOD2, SUOX+, TGFB1+, TNF+, TRAF1, TRAP1, USF1, VDR+

 

Note: +:multiple variants sequenced for this gene, ~:intronic location near this gene

Ready to Get Started?

To order the Avantra Genetics Migraine Panel, a healthcare professional (HCP) must complete and sign the Service Requisition Form. HCPs can complete the online form and directly submit to Avantra Genetics or print and fax the paper form. Patients can print the paper form to bring to their next HCP appointment or share the link to the online form with their HCP. Once we have received the completed form, we will contact the patient for payment and send them a Sample Collection Kit.

Frequently Asked Questions

Why is a healthcare professional's signature needed to order?

Avantra Genetics genetic services provide genetic information that is best reviewed by a healthcare professional (HCP). Avantra Genetics panels contain specific information about genetic variants as well as links to publicly available genetic references, that may provide additional information to the HCP which they can choose to incorporate to make informed treatment decisions for their patients.

How do I submit a sample?

After we receive an order for an Avantra Genetics panel, we will mail a saliva collection kit to the patient at the address provided on the Service Requisition Form. This kit includes instructions for collecting, labeling, and mailing the sample to our laboratory.

How does Avantra collect payment?

We will send instructions for completing online payment to the patient’s email address provided on the Service Requisition Form. We accept all major credit cards as well as PayPal.

Please note that we will not process any samples until payment has been received.

Who will receive the results?

Results are delivered to the healthcare professional who ordered the service in order to provide them with the opportunity to discuss the results and any follow-up testing with the patient.